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What creatinine level signifies kidney failure?

Creatinine is a chemical by-product produced as tissues break down during regular muscle metabolism. It is created, filtered by the kidneys, and then eliminated through urine. The amount of creatinine in your blood is a sign of how well your kidneys are working. Creatinine clearance rate refers to the kidneys' ability to remove creatinine from the bloodstream and render it creatinine-free (CCR). The glomerular filtration rate, or CCR, is determined by the rate at which blood passes through the kidneys (GFR).Body size, activity level, and medications are all factors that influence the amount of creatinine in the kidneys. Men's kidney creatinine levels are typically between 0.6 and 1.2 milligrams/deciliter (mg/dL). Women's levels are reported to be between 0.5 and 1.1 mg/dL. What is the significance of creatinine clearance? Because measuring GFR directly is challenging, clinicians use creatinine clearance as a proxy for GFR and, as a result, renal function. In a healthy a